Commvault by design is meant to be hardware agnostic and can be configured however you like.
In terms of creating a single 600TB share is this a recommended approach by Huawei?
Although a single Share can be shared with all MediaAgent using SMB, it is still a single point of failure, so if you lose this share you will lose all access to backup and restore.
Splititng the Volume into smaller share will help, but please bare in mind if you do split into smaller share and you are utilzing Commvault Deduplication and any one of the share is offline, restore might be impacted as the referenced blocks might reside on the volume.
However for backups, when a single Mount Path is offline, MediaAgent will detect this and will attempt to re-write new baseline data to other Mount Path that are still available. So what that means is backup moving forward (when one Mount Path is offline) will still work, but historical backups might not be restorable until you bring the Mount Path back online
Feel free to reach out if you have any question